Mechanisms of redox metabolism and cancer cell survival during extracellular matrix detachment
نویسندگان
چکیده
منابع مشابه
Induction of autophagy during extracellular matrix detachment promotes cell survival.
Autophagy has been proposed to promote cell death during lumen formation in three-dimensional mammary epithelial acini because numerous autophagic vacuoles are observed in the dying central cells during morphogenesis. Because these central cells die due to extracellular matrix (ECM) deprivation (anoikis), we have directly interrogated how matrix detachment regulates autophagy. Detachment induce...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2018
ISSN: 0021-9258
DOI: 10.1074/jbc.tm117.000260